Clinical Trials

Many of our physicians are also leading researchers in their specialties, making breakthroughs and contributing to discoveries that are shaping their fields. Their research may offer some of our patients the additional benefit of having access to treatments that are under review in clinical trials.

Enrolling in a study does not always include testing a new treatment. Participating in a study can be as simple as answering a phone survey every few months to help doctors better understand healthy development, the effectiveness of prevention behaviors or the progression of a disease state. You will never be enrolled in a clinical study without your consent, and our physicians will give you complete information about a study that interests you before you choose whether to take part.

Learn more on the Washington University Physicians website:
Read the frequently asked questions about clinical trials »

Get notifications from Volunteer for Health:
Register to hear when you may have matched to a study »

Find a study in the National Institutes of Health (NIH) registry:
Search studies in all specialties at Washington University »

Find a clinical trial in obstetrics and gynecology

To request more information about a study below, you may email

Research: Contraception & Family Planning

  • L105: A Phase 3, Multicenter, Open-Label Study of a Levonorgestrel 52 mg Intrauterine System for the Treatment of Heavy Menstrual Bleeding

    PI: David Eisenberg, MD

    The purpose of this study is to evaluate if Liletta IUD (a hormonal intrauterine device) is a safe and effective treatment for women with very heavy menstrual bleeding. Participants must be female, 18-50 years old, and must report heavy periods when not using hormonal contraception or a copper IUD. They will be asked to come to the clinic for up to 8 study visits.

    Contact: Tracy Burger, RN, BSN
    314-747-1390 |

  • UPFRONT: Multi-component implementation of shared decision making (SDM) for uterine fibroids across socioeconomic strata

    PI: Tessa Madden, MD

    Uterine fibroids are prevalent among adult women, with nearly half of reproductive-age women experiencing them.  There are many options available to treat uterine fibroids, each with their own tradeoffs.  Because of this, patient preference plays a large role in the treatment decision.  We plan to use a tool called an Option Grid, which is designed to facilitate conversation between patients and providers about treatment options that are aligned with patient preferences.  We hope to gain an understanding of how an Option Grid can be implemented and sustained in diverse clinical settings.

    We will enroll two groups of participants: patients seeking treatment with our physicians for new or recurrent symptoms of uterine fibroids (e.g. heavy menstrual bleeding, pelvic pressure or pain, etc.) and physicians who provide care to these patients.

    Contact: Tracy Burger, RN, BSN
    314-747-1390 |