Clinical Trials

Many of our physicians are also leading researchers in their specialties, making breakthroughs and contributing to discoveries that are shaping their fields. Their research may offer some of our patients the additional benefit of having access to treatments that are under review in clinical trials.

Enrolling in a study does not always include testing a new treatment. Participating in a study can be as simple as answering a phone survey every few months to help doctors better understand healthy development, the effectiveness of prevention behaviors or the progression of a disease state. You will never be enrolled in a clinical study without your consent, and our physicians will give you complete information about a study that interests you before you choose whether to take part.

Learn more on the Washington University Physicians website:
Read the frequently asked questions about clinical trials »

Get notifications from Volunteer for Health:
Register to hear when you may have matched to a study »

Find a study in the National Institutes of Health (NIH) registry:
Search studies in all specialties at Washington University »

Find a clinical trial in obstetrics and gynecology

To request more information about a study below, you may email

Research: Contraception & Family Planning

  • EPIC (Effectiveness of Prolonged Use of IUD/Implanon)

    Colleen McNicholas, MD

    The progesterone-containing intrauterine device (Mirena® or LNG-IUD) is FDA-approved for 5 years of use and the subdermal contraceptive implant (Implanon® or ENG implant) is approved for 3 years. However, there is data in the literature that these methods may be highly effective for longer durations. This prospective cohort study will evaluate 675 LNG-IUD users and 675 ENG implant users who are within 6 months of expiration or beyond the end of the FDA-approved duration.

    Contact: Lisa Muench
    314-362-4317 |

  • EPIC Assessing Ovarian Function During Prolonged Implant Use

    Colleen McNicholas, DO

    The purpose of this research study is to evaluate how the ovaries may be functioning while using the the Implanon®/Nexplanon® during the three years beyond the FDA approved duration. We will measure the activity of the ovary by checking progesterone levels (naturally occurring hormone found in the body) in blood. We will also check the etonogestrel levels (the hormone found in the implant). Lastly, data about bleeding patterns will be collected for 30 days.

    Contact: Lisa Muench
    314-362-4317 |