To fertilize an egg, human sperm must undergo a process in which the membrane becomes more negative inside. The ion channel responsible for this membrane hyperpolarization has long been unclear. In this publication, the Santi and Denton labs describe a screen to identify inhibitors of a strong candidate – the sperm-specific potassium channel SLO3. They […]
Santi Lab publishes “A selective inhibitor of the sperm-specific potassium channel SLO3 impairs human sperm function” (Links to an external site)












































