Debbie Frank was awarded the Research Support Award

Debbie Frank joined the Department of Obstetrics and Gynecology as the Scientific Editor in 2012 and was promoted to Senior Scientific Editor in 2021. In this role, she helps faculty members, medical fellows, residents, post-doctoral fellows, and graduate students prepare research manuscripts, grant proposals, and fellowship applications. Debbie’s primary goal is to facilitate clear and […]

Viju Gupta, PhD & Audrey Johnston, MBA graduated from the Emerging Leaders Program

Viju Gupta, PhD and Audrey Johnston, MBA from the Center for Reproductive Health Sciences celebrated their graduation as two of only 30 WashU staff members in the inaugural cohort of the Emerging Leaders Program, sponsored by the Institute for Leadership Excellence. This is a 9-month, competitive program for WashU Staff members who manage individual contributors […]

CRepHS at Immunology 2024

The Annual Meeting of the American Association of Immunologists (Immunology 2024) was held in Chicago, Illinois! From our team, Dr. Nardhy Gomez-Lopez, Dustyn Levenson, and Valeria Garcia-Flores!

Kaci Martin receives the Rosalind Kornfeld Student Leadership Award

PhD student Kaci Martin from the Frolova lab received the Rosalind Kornfeld Student Leadership Award from the Academic Women’s Network last week. This award is given to a graduate or medical student that has demonstrated outstanding leadership in service to, or advancement of women within the community. Our Department Chair, Dr. Dineo Khabele, was there […]

CRepHS takes home two awards

Awards Galore! PhD student Kaci Martin from the Frolova lab received two awards from the Division of Biology and Biomedical Sciences last week – the Student Group Member of the Year Award and the Excellence in Research Award. If that wasn’t enough, Kaci’s PI, Assistant Professor Antonina Frolova, MD, PhD received the Outstanding Faculty Mentor. […]

CRepHS hosts first-ever game table tournament

The Center for Reproductive Health Sciences recently hosted its first Game Table Tournament! Thanks to the Wellness Champion Fund from HR, the CRepHS breakroom received a combination game table complete with ping pong, foosball, and air hockey. We then pitted lab-mates and faculty against one another in an epic event! Please congratulate our champions! – […]

CRepHS at GRS

The Center for Reproductive Health Sciences was well represented this week at the 29th Annual Graduate Research Symposium, hosted by the Washington University in St. Louis Graduate Student Senate on the Danforth Campus. From left to right: Postdoctoral Research Associates Juan Ferreira, PhD (Santi Lab) and Sara Pietroforte, PhD (Amargant i Riera Lab) participated as […]

Gomez-Lopez lab trainee receives a 2024 AAI Trainee Abstract Award

MD/PhD student Dustyn Levenson in the Gomez-Lopez Lab was selected to present her work in a Block Symposium at “Immunology2024,” the annual meeting of the American Association of Immunologists (AAI), and will receive a 2024 AAI Trainee Abstract Award. We are incredibly proud of her hard work! Congratulations, Dustyn! #AAI2024

Update to Wang’s reproductive health research

Yong Wang, PhD, Professor of Obstetrics and Gynecology, Electrical and System Engineering, Radiology, and Biomedical Engineering, in collaboration with Valerie Ratts, MD, Professor of Reproductive Endocrinology and Infertility, is making strides in discovery related to his project titled “Understanding Uterine Function and How it Relates to Reproductive Health.” This project was recently expanded to investigate […]

“Dr. Gomez-Lopez on “Deciphering maternal-fetal cross-talk in the human placenta during parturition using single-cell RNA sequencing”

On the weekly Science Podcast, producer Kevin McLean talks with researcher Nardhy Gomez-Lopez, a professor in the department of obstetrics and gynecology and pathology and immunology in the Center for Reproductive Health Sciences at Washington University School of Medicine in St. Louis. The two discuss signaling between fetus and mother during childbirth and how understanding this crosstalk may one […]

Dr. Gomez-Lopez published in Science Translational Medicine

An atlas revealing the activity of individual placental cells during childbirth offers insight on what happens at the maternal-fetal interface during term labor, according to a study supported by the National Institutes of Health (NIH). The atlas provides a single-cell analysis of the human placenta and its surrounding membranes and is the first to use […]

Dr. Sassin presents at CRepHS Seminar Series

The Center for Reproductive Health Sciences (CRepHS) welcomed visiting speaker Alexa Sassin, MD, Assistant Professor, Department of Obstetrics and Gynecology, Baylor College of Medicine, on Jan. 5th as part of the CRepHS Seminar Series. Dr. Sassin’s impactful presentation on Polycystic Ovarian Syndrome (PCOS) research was well-received by seminar attendees over Zoom and in person at BJC-IH. […]

Collaborative Open House a success for CRepHS/CWHE

The Center for Reproductive Health Sciences (CRepHS) and the Center for Women’s Health Engineering (CWHE) hosted an open house event on December 5, 2023. At this collaborative event held on the Medical Campus, more than 70 attendees from the McKelvey School of Engineering and the School of Medicine were able to network and learn about reproductive health research, education […]

Dr. Gomez-Lopez published in eBioMedicine

Dr. Nardhy Gomez-Lopez’s paper “Blockade of IL-6R prevents preterm birth and adverse neonatal outcomes” was published in eBioMedicine. Evidence before this study Prematurity remains as the leading cause of neonatal morbidity and mortality before five years of age globally. One in every three preterm infants is born to a pregnant individual with inflammation of the […]

Portrait of Dr. Sarah England Unveiled

Sarah England, PhD, Alan A. and Edith L. Wolff Professor of Medicine, Vice Chair of Research for the Department of Obstetrics and Gynecology, and Director of the Center for Reproductive Health Sciences at Washington University School of Medicine, recently received distinctive recognition of her exceptional research accomplishments and service in the field of obstetrics and […]

England Elected to National Academy of Medicine (Links to an external site)

Reproductive biologist Sarah K. England, PhD, and two others from Washington University School of Medicine in St. Louis, have been elected to the National Academy of Medicine, a part of the National Academy of Sciences. Membership in the organization is one of the highest honors in the fields of health and medicine in the United […]

R01 Grant Recipients

Congratulations to Peinan Zhao, PhD, Assistant Professor of Obstetrics and Gynecology, Washington University School of Medicine in St. Louis, on receiving a new five year R01 grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) with co-principal investigator Molly Stout, MD, MS, Associate Professor of Obstetrics and Gynecology, University of Michigan. The R01 […]

R00 grant for ovarian aging research

Farners Amargant i Riera, PhD, was awarded an R00 for her project titled, “Mechanotransduction mechanisms of ovarian aging.” Dr. Amargant i Riera will examine how the increase in the biomechanical properties of the ovary with age are spatially and hormonally regulated and how they influence follicle transcriptome through the YAP1 pathway. Overall, the proposed studies […]

2023 National Postdoc Appreciation Week

Happy National Postdoc Appreciation Week! WashU has a diverse community of over 850 postdocs from different parts of the world.  Their commitment to research, teaching, and mentorship not only enhances the academic community at Washington University, but also plays a pivotal role in advancing science, technology, and scholarship across the country and around the world. We […]

R21 grant for labor research

Antonina Frolova, MD, PhD, Assistant Professor of Obstetrics and Gynecology, was awarded an R21 for her project titled, “Metabolic mechanisms of uterine contractility in labor.” The objective of the project is to determine the mechanisms driving obesity-related labor dysfunction. This research may lead to new options for pharmacologic and behavioral interventions to optimize myometrial energy […]

R01 grant for research on maternal opioid use

Jeannie Kelly, MD, MS, Associate Professor of Obstetrics and Gynecology, and Yong Wang, PhD, Professor of Obstetrics and Gynecology, were awarded an R01 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The project is titled, “The Opioid in Pregnancy: Imaging of Oxygenation, Inflammation, and Development in Brain & Placenta […]

Dr. Mullen receives 2023 Victoria’s Secret Global Fund for Women’s Cancers Career Development Award

Dr. Maggie Mullen has been awarded grant funding through the 2023 Victoria’s Secret Global Fund for Women’s Cancers Career Development Award, in partnership with Pelotonia & AACR,  Targeting platinum chemotherapy resistance in ovarian cancer. **This two-year grant starts in September.** These accomplishments are impossible without our amazing research and clinical teams and the sponsorship of our […]

American Cancer Society grant

Sumegha Mitra, PhD, Associate Professor of Obstetrics and Gynecology, received a 3-year, $754,414 Research Scholar Grant, RSG-22-070-01-TBE, from the American Cancer Society (ACS) to study high-grade serous ovarian cancer (HGSOC). Dr. Mitra’s ACS-funded project is titled “Protein Homeostasis Network Regulates Oncogenic Signaling in High-Grade Serous Ovarian Cancer.” “My American Cancer Society grant will study how adaptive […]

Registration Now Open for the 48th Annual Symposium

Eric P. Newman Education Center @ Washington University Medical CenterOctober 19, 2023 8:00 AM – October 20, 2023 3:30 PM Coordinator Michelle R Padgett, MS, ATC, Washington University CME Agenda This conference is offered as an in-person course only. Thursday, October 19, 2023   7:30am Registration & Continental Breakfast    8:10     Welcome – Makeba Williams, MD, NCMP Session I […]

Summertime scientific successes for Santi Lab

The lab of Celia Santi, MD, PhD, has been busy this summer with scientific discussions and networking opportunities! Dr. Santi presented her lab’s work on non-hormonal contraception during the “Male Contraceptive” session at the Society for the Study of Reproduction (SSR) 56th Annual Meeting. The “Reproductive Sciences: From Innovation to Impact” SSR meeting took place in Ottawa, Canada, […]

Compadre, van Biljon publish a co-first author article in Clinical Cancer Research

Amanda Compadre, MD, and Lily van Biljon recently published an article in Clinical Cancer Research titled “RAD51 Foci as a Biomarker Predictive of Platinum Chemotherapy Response in Ovarian Cancer.” This paper demonstrates that RAD51 foci are a robust marker of platinum chemotherapy response and survival in ovarian cancer. This research was led by Mary (Maggie) Mullen, MD. […]

Frolova named Doris Duke program scholar

Antonina (Toni) Frolova, MD, PhD, a maternal-fetal medicine physician and Assistant Professor of Obstetrics and Gynecology, applied and was selected to be a scholar in the Doris Duke COVID-19 Fund to Retain Clinical Scientists (CFRCS) program at Washington University School of Medicine. As an early career physician-scientist, the program will benefit Dr. Frolova’s navigation of this stage […]

Magdalena Nelson was awarded the WashU School of Medicine Research Support Award

Magdalena Nelson, MBA, Director of Research and Business Administration in the Department of Obstetrics and Gynecology, is this year’s recipient of the WashU School of Medicine Research Support Award. This award from the medical school recognizes employees for exceptional performance or cooperation, outstanding leadership, and superior quality of service. As a distinguished honors awardee, Magdalena was […]

WashU Gynecologic Oncology Tissue Bank celebrated collecting its 100th tissue sample

The WashU Gynecologic Oncology Tissue Bank celebrated collecting its 100th tissue sample for bench-to-bedside research endeavors. Along with this notable achievement in specimen collection, the labs of Drs. Dineo Khabele and Maggie Mullen have instituted a newly organized process for collecting and managing samples, and are developing research on patient-derived organoids. “We couldn’t have done it without the hard […]

CRepHS celebrates its graduates

The Center for Reproductive Health Sciences celebrated its graduates! Congrats to all and good luck with your future endeavors!

Mullen Lab receives honorable mentions for best oral and poster presentations!

The Mullen lab at the Siteman Cancer Center’s Center for Genome Integrity retreat. Viju Gupta, PhD from the Khabele lab also presented! Dr. Amanda Compadre received an honorable mention for the best Oral Presentation and Olivia Graham and Jeimmy Rodriguez of our Tissue Bank got an honorable mention for the best poster presentation. Big wins […]

CRepHS and GynOnc celebrate new research progress

The WashU Gynecologic Oncology Tissue Bank just celebrated collecting its 100th tissue sample for bench-to-bedside research endeavors. Along with this notable achievement in specimen collection, the labs of Drs. Dineo Khabele and Maggie Mullen with the Center for Reproductive Health Sciences (CRepHS) and the Division of Gynecologic Oncology (GynOnc) have instituted a newly organized process for collecting and managing […]

CRepHS was awarded at the 70th SRI Meeting

Members of CRepHS recently voyaged to Brisbane, Australia to present at and attend the 70th Annual Meeting of the Society for Reproductive Investigation (SRI). Sicheng Wang and Yiqi Lin (Wang Lab) both won the SRI President’s Presenter’s Award, Patricia Strutz, MD, MSCI (England Lab) and Zhexian Sun (Wang Lab) both won the Poster Award, and […]

Dr. Wang cited in “New, non-invasive imaging tool maps uterine contractions during labor”

“The study team, led by Yong Wang, Ph.D., and Alan Schwartz, M.D., Ph.D., at Washington University in St. Louis, and Alison Cahill, M.D., at the University of Texas at Austin, initially developed EMMI using a sheep model and reported their findings in Science Translational Medicine. In the new study, the team tailored EMMI for human clinical use […]

Promising new researcher obtains prestigious fellowship award

Juan Ferreira, PhD, postdoctoral research associate in the Santi Lab, recently earned a fellowship award from the Lalor Foundation for his research on a new assay to evaluate sperm fertilization capacity in infertile patients. “I would like to express thanks to Drs. England, Blanco, Lishko and Frank for their support of this project,” Ferreira states, “and […]

WashU Named in Top 10 in Blue Ridge Ranking

WashU’s Deptartment of OBGYN has once again achieved a US TOP 10 RANKING! Funds awarded to our department by the National Institutes of Health totaled $6.4M in 2022, as reported by Blue Ridge Institute for Medical Research #BRIMR. Congrats to our amazing & dedicated research teams!

CRepHS Valentines Bake-Off

The members of CRepHS held a Valentine’s Bake-Off and card-making party. Photos courtesy of Julie Emmerich!

Santi Lab publishes “A selective inhibitor of the sperm-specific potassium channel SLO3 impairs human sperm function” (Links to an external site)

To fertilize an egg, human sperm must undergo a process in which the membrane becomes more negative inside. The ion channel responsible for this membrane hyperpolarization has long been unclear. In this publication, the Santi and Denton labs describe a screen to identify inhibitors of a strong candidate – the sperm-specific potassium channel SLO3. They […]

Santi Lab receives funding to further develop non-hormonal female contraceptives

Celia Santi, MD, Ph.D., recently received a two-year grant from the Bill & Melinda Gates Foundation. The $435,000 award, beginning November 2022, will support her lab’s efforts in screening and characterizing a new class of female-controlled non-hormonal contraceptive agents using in vitro and in vivo assays. Dr. Santi’s research project is titled, “SLO3 inhibitors: a […]

COLLABORATORS IN WOMEN’S HEALTH RESEARCH

Two new trainees recently began their fellowships through the Department of Ob/Gyn’s T32 training grant titled, “Clinical Outcomes Research Training in Female Lower Urinary Tract Disorders,” led by Co-Principal Investigators Jerry Lowder, MD, MSc, and Siobhan Sutcliffe, PhD, and funded through the NIH NIDDK. Dr. Victoria Leigh Brown received her PhD in Anthropology from Binghamton […]

Congratulations, Dr. Ferreira! (Links to an external site)

PhD Candidate Juan Ferreira from Dr. Celia Santi’s lab successfully defended his thesis in January 2022, entitled “SLO2.1 channels: a new molecular mechanism to regulate uterine excitability.” Congratulations, Dr. Ferreira!

2nd annual CRepHS Symposium

The Long Road to Fertilization: From the Bench to the Bedside and Back Again