Category: CRepHS Research News

WashU Medicine OB-GYN Chair, Dr. Dineo Khabele, and Postdoctoral Research Associate, Bisi Fashemi, PhD, recently presented at the Keystone Regenerative Biology of the Female Reproductive System meeting. Dr. Fashemi received a travel award to present a poster and talk on the project entitled “Single-Cell Signatures of High-Grade Serous Ovarian Cancer Patient-Derived Organoids”.  Dr. Khabele sat […]

Nardhy Gomez-Lopez, PhD, was elected to the Publications Committee of the American Association of Immunologists. Congrats to Dr. Gomez-Lopez! The term begins on July 1, 2025. To read more about the election results, please visit the link below. Congratulations to everyone who was elected!

The Khabele lab recently published a new manuscript in BMC Cancer, titled “The Tie2 antagonist rebastinib reduces ovarian cancer growth in a syngeneic murine model.” Gupta VG, Roby KF, Pathak HB, Godwin AK, Gunewardena S, Khabele D. The Tie2 antagonist rebastinib reduces ovarian cancer growth in a syngeneic murine model. BMC Cancer. 2025 Feb 11;25(1):233. […]

On average in the US, 1 in 10 babies is born prematurely and, in many cases, the cause is unknown. However, there could be many contributing factors, nearly 40% of pregnant people who deliver before 37 weeks exhibit chronic placental inflammation, which happens when the mother’s immune system attacks the placenta. If we understood this […]

The Gomez-Lopez lab’s recently published article in The Journal of Immunology has been featured as a top read by the editor for the December 1st issue. Notably, only two articles are selected per issue for this recognition. Congratulations to the Gomez-Lopez lab!

PhD graduate student Kevin Prifti from the Frolova lab was recently awarded the CRepHS Biannual Best Paper Award, a friendly competition for first-author trainees within the Center. Kevin’s paper was also chosen as “Editor’s choice” by the journal in which he published, Biology of Reproduction. Congratulations, Kevin! Be sure to read the publication here: https://pubmed.ncbi.nlm.nih.gov/38857377/ – Citation: Prifti […]

Nardhy Gomez-Lopez, PhD presented at the WashU Medicine ODEI Faculty Showcase! This event was held in honor of Latiné/Hispanic Heritage Month. Our partners included the WashU Medicine Office of Diversity, Equity, and Inclusion(ODEI), the Department of Obstetrics & Gynecology, SOMOS WashU, the WashU COTAD Chapter, and the WashU LMSA Chapter. “From Passion to Purpose: My Journey, Inspirations, […]

Washington University in St. Louis’ Department of Obstetrics & Gynecology hosted our 2024 Dr. Jacob Probstein Visiting Professor Dr. Kristina Adams Waldorf, Professor of Obstetrics and Gynecology at the University of Washington. She presented her research entitled, “Unraveling Biology at the Maternal-Fetal Interface:  Preterm Birth Studies in a Nonhuman Primate”.

Nardhy Gomez-Lopez, PhD, a professor of obstetrics & gynecology at Washington University School of Medicine in St. Louis, has received a four-year, $500,000 award from the Burroughs Wellcome Fund to further research into the immunobiology of the maternal-fetal interface and identify biomarkers to predict preterm labor and birth. One in 10 babies is born prematurely and, in many cases, […]

The Annual Meeting of the American Association of Immunologists (Immunology 2024) was held in Chicago, Illinois! From our team, Dr. Nardhy Gomez-Lopez, Dustyn Levenson, and Valeria Garcia-Flores!

PhD student Kaci Martin from the Frolova lab received the Rosalind Kornfeld Student Leadership Award from the Academic Women’s Network last week. This award is given to a graduate or medical student that has demonstrated outstanding leadership in service to, or advancement of women within the community. Our Department Chair, Dr. Dineo Khabele, was there […]

Awards Galore! PhD student Kaci Martin from the Frolova lab received two awards from the Division of Biology and Biomedical Sciences last week – the Student Group Member of the Year Award and the Excellence in Research Award. If that wasn’t enough, Kaci’s PI, Assistant Professor Antonina Frolova, MD, PhD received the Outstanding Faculty Mentor. […]

The Center for Reproductive Health Sciences recently hosted its first Game Table Tournament! Thanks to the Wellness Champion Fund from HR, the CRepHS breakroom received a combination game table complete with ping pong, foosball, and air hockey. We then pitted lab-mates and faculty against one another in an epic event! Please congratulate our champions! – […]

The Center for Reproductive Health Sciences was well represented this week at the 29th Annual Graduate Research Symposium, hosted by the Washington University in St. Louis Graduate Student Senate on the Danforth Campus. From left to right: Postdoctoral Research Associates Juan Ferreira, PhD (Santi Lab) and Sara Pietroforte, PhD (Amargant i Riera Lab) participated as […]

MD/PhD student Dustyn Levenson in the Gomez-Lopez Lab was selected to present her work in a Block Symposium at “Immunology2024,” the annual meeting of the American Association of Immunologists (AAI), and will receive a 2024 AAI Trainee Abstract Award. We are incredibly proud of her hard work! Congratulations, Dustyn! #AAI2024

Yong Wang, PhD, Professor of Obstetrics and Gynecology, Electrical and System Engineering, Radiology, and Biomedical Engineering, in collaboration with Valerie Ratts, MD, Professor of Reproductive Endocrinology and Infertility, is making strides in discovery related to his project titled “Understanding Uterine Function and How it Relates to Reproductive Health.” This project was recently expanded to investigate […]

On the weekly Science Podcast, producer Kevin McLean talks with researcher Nardhy Gomez-Lopez, a professor in the department of obstetrics and gynecology and pathology and immunology in the Center for Reproductive Health Sciences at Washington University School of Medicine in St. Louis. The two discuss signaling between fetus and mother during childbirth and how understanding this crosstalk may one […]

An atlas revealing the activity of individual placental cells during childbirth offers insight on what happens at the maternal-fetal interface during term labor, according to a study supported by the National Institutes of Health (NIH). The atlas provides a single-cell analysis of the human placenta and its surrounding membranes and is the first to use […]

The Center for Reproductive Health Sciences (CRepHS) welcomed visiting speaker Alexa Sassin, MD, Assistant Professor, Department of Obstetrics and Gynecology, Baylor College of Medicine, on Jan. 5th as part of the CRepHS Seminar Series. Dr. Sassin’s impactful presentation on Polycystic Ovarian Syndrome (PCOS) research was well-received by seminar attendees over Zoom and in person at BJC-IH. […]

The Center for Reproductive Health Sciences (CRepHS) and the Center for Women’s Health Engineering (CWHE) hosted an open house event on December 5, 2023. At this collaborative event held on the Medical Campus, more than 70 attendees from the McKelvey School of Engineering and the School of Medicine were able to network and learn about reproductive health research, education […]

Peinan Zhao, PhD, Assistant Professor of Obstetrics and Gynecology, Washington University School of Medicine in St. Louis, received a new five year R01 grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) with co-principal investigator Molly Stout, MD, MS, Associate Professor of Obstetrics and Gynecology, University of Michigan. The R01 grant provides […]

Farners Amargant i Riera, PhD, was awarded an R00 for her project titled, “Mechanotransduction mechanisms of ovarian aging.” Dr. Amargant i Riera will examine how the increase in the biomechanical properties of the ovary with age are spatially and hormonally regulated and how they influence follicle transcriptome through the YAP1 pathway. Overall, the proposed studies […]

Happy National Postdoc Appreciation Week! WashU has a diverse community of over 850 postdocs from different parts of the world.  Their commitment to research, teaching, and mentorship not only enhances the academic community at Washington University, but also plays a pivotal role in advancing science, technology, and scholarship across the country and around the world. We […]

Antonina Frolova, MD, PhD, Assistant Professor of Obstetrics and Gynecology, was awarded an R21 for her project titled, “Metabolic mechanisms of uterine contractility in labor.” The objective of the project is to determine the mechanisms driving obesity-related labor dysfunction. This research may lead to new options for pharmacologic and behavioral interventions to optimize myometrial energy […]

Jeannie Kelly, MD, MS, Associate Professor of Obstetrics and Gynecology, and Yong Wang, PhD, Professor of Obstetrics and Gynecology, were awarded an R01 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The project is titled, “The Opioid in Pregnancy: Imaging of Oxygenation, Inflammation, and Development in Brain & Placenta […]

Sumegha Mitra, PhD, Associate Professor of Obstetrics and Gynecology, received a 3-year, $754,414 Research Scholar Grant, RSG-22-070-01-TBE, from the American Cancer Society (ACS) to study high-grade serous ovarian cancer (HGSOC). Dr. Mitra’s ACS-funded project is titled “Protein Homeostasis Network Regulates Oncogenic Signaling in High-Grade Serous Ovarian Cancer.” “My American Cancer Society grant will study how adaptive […]

The lab of Celia Santi, MD, PhD, has been busy this summer with scientific discussions and networking opportunities! Dr. Santi presented her lab’s work on non-hormonal contraception during the “Male Contraceptive” session at the Society for the Study of Reproduction (SSR) 56th Annual Meeting. The “Reproductive Sciences: From Innovation to Impact” SSR meeting took place in Ottawa, Canada, […]

Amanda Compadre, MD, and Lily van Biljon recently published an article in Clinical Cancer Research titled “RAD51 Foci as a Biomarker Predictive of Platinum Chemotherapy Response in Ovarian Cancer.” This paper demonstrates that RAD51 foci are a robust marker of platinum chemotherapy response and survival in ovarian cancer. This research was led by Mary (Maggie) Mullen, MD. […]

The Center for Reproductive Health Sciences celebrated its graduates! Congrats to all and good luck with your future endeavors!

Members of CRepHS recently voyaged to Brisbane, Australia to present at and attend the 70th Annual Meeting of the Society for Reproductive Investigation (SRI). Sicheng Wang and Yiqi Lin (Wang Lab) both won the SRI President’s Presenter’s Award, Patricia Strutz, MD, MSCI (England Lab) and Zhexian Sun (Wang Lab) both won the Poster Award, and […]

Juan Ferreira, PhD, postdoctoral research associate in the Santi Lab, recently earned a fellowship award from the Lalor Foundation for his research on a new assay to evaluate sperm fertilization capacity in infertile patients. “I would like to express thanks to Drs. England, Blanco, Lishko and Frank for their support of this project,” Ferreira states, “and […]

WashU’s Deptartment of OBGYN has once again achieved a US TOP 10 RANKING! Funds awarded to our department by the National Institutes of Health totaled $6.4M in 2022, as reported by Blue Ridge Institute for Medical Research #BRIMR. Congrats to our amazing & dedicated research teams!

The members of CRepHS held a Valentine’s Bake-Off and card-making party. Photos courtesy of Julie Emmerich!

Celia Santi, MD, Ph.D., recently received a two-year grant from the Bill & Melinda Gates Foundation. The $435,000 award, beginning November 2022, will support her lab’s efforts in screening and characterizing a new class of female-controlled non-hormonal contraceptive agents using in vitro and in vivo assays. Dr. Santi’s research project is titled, “SLO3 inhibitors: a […]